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GPCR - G protein mediated signalling




G protein–coupled receptors (GPCRs) which constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses.

G proteins, also known as guanine nucleotide-binding proteins, are a family of proteins that act as molecular switches inside cells, and are involved in transmitting signals from a variety of stimuli outside a cell to its interior.

G proteins located within the cell are activated by G protein-coupled receptors (GPCRs) that span the cell membrane.

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